Iron dextran

Iron Dextran is a type of intravenous iron supplement used to treat iron deficiency anemia, a condition characterized by low levels of red blood cells due to a lack of iron. Iron dextran is often used when oral iron supplements are ineffective or cannot be used.

Composition

Iron dextran is a complex of iron (III) hydroxide and dextran, a type of polysaccharide. The iron is present in a trivalent form, which is the form of iron needed for the production of hemoglobin, the molecule in red blood cells that carries oxygen.

Uses

Iron dextran is used to treat iron deficiency anemia in patients who cannot tolerate or absorb oral iron supplements. It is also used in patients with chronic kidney disease who are receiving hemodialysis and are also receiving supplemental erythropoietin, a hormone that stimulates the production of red blood cells.

Administration

Iron dextran is administered intravenously, either as a slow injection or as an infusion. The dose and frequency of administration depend on the patient's iron levels and overall health status.

Side Effects

Common side effects of iron dextran include nausea, vomiting, diarrhea, and pain at the injection site. Serious side effects can include allergic reactions, low blood pressure, and iron overload, which can lead to damage to the liver and other organs.

Contraindications

Iron dextran should not be used in patients with iron overload or hemochromatosis, a condition characterized by excessive absorption of dietary iron. It should also be used with caution in patients with liver disease or any condition that can increase the risk of iron overload.

See Also

• Iron deficiency anemia
• Iron supplement
• Hemodialysis
• Erythropoietin