Inferior frontal junction

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Inferior Frontal Junction

The Inferior Frontal Junction (IFJ) is a region of the brain located in the frontal lobe, specifically at the intersection of the inferior frontal sulcus and the precentral sulcus. It is associated with various cognitive functions, including attention control, task switching, and working memory.

Anatomy[edit | edit source]

The IFJ is situated in the Brodmann area 44 and Brodmann area 45, which are part of the Broca's area. It is located in the dorsolateral prefrontal cortex, which is involved in executive functions. The IFJ is not a distinct anatomical structure, but a functional one, defined by its role in cognitive processes.

File:Inferior Frontal Junction.png
Location of the Inferior Frontal Junction in the brain

Function[edit | edit source]

The IFJ plays a crucial role in cognitive control, which includes processes such as task switching, attention control, and working memory. It is also involved in language processing, particularly in syntactic and semantic processing.

Task Switching[edit | edit source]

The IFJ is involved in the ability to switch between different tasks, a process known as task switching. This involves disengaging from one task and engaging in another, which requires cognitive flexibility.

Attention Control[edit | edit source]

The IFJ is also associated with attention control, the ability to selectively concentrate on a specific aspect of information while ignoring other perceivable information.

Working Memory[edit | edit source]

The IFJ contributes to working memory, the system responsible for temporarily holding and manipulating information.

Clinical Significance[edit | edit source]

Damage or dysfunction in the IFJ can lead to cognitive deficits, particularly in task switching, attention control, and working memory. It has been implicated in various neurological and psychiatric disorders, including ADHD, schizophrenia, and dementia.

See Also[edit | edit source]

References[edit | edit source]



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Contributors: Prab R. Tumpati, MD