Interferon kappa

Interferon kappa (IFN-κ) is a type of interferon that is part of the Type I interferon family. It is a cytokine that plays a crucial role in the immune response against viral infections.

Function

Interferon kappa is produced by keratinocytes, the predominant cell type in the epidermis. It is involved in the immune response by inducing the expression of interferon-stimulated genes (ISGs) that have antiviral properties.

Structure

The structure of interferon kappa is similar to other type I interferons. It is a protein that is composed of approximately 200 amino acids.

Clinical significance

Interferon kappa has been implicated in several diseases, including psoriasis, lupus, and cancer. It is also being studied for its potential use in the treatment of hepatitis C and HIV.

Research

Research on interferon kappa is ongoing, with studies focusing on its role in the immune response, its potential therapeutic uses, and its involvement in disease.

See also

• Interferon
• Type I interferon
• Cytokine
• Immune system

References

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