Interleukin-28

Interleukin-28 (IL-28), also known as Interferon lambda 2 (IFNλ2), is a type of Cytokine that plays a crucial role in the immune response of the body. It is a part of the Interferon family and is produced by the immune cells in response to viral infections.

Function

IL-28 is involved in the immune response against viral infections. It is produced by immune cells, such as Dendritic cells and Macrophages, in response to viral infections. IL-28 binds to a specific receptor on the surface of cells, triggering a cascade of events that lead to the activation of the immune response. This includes the production of other cytokines, the activation of immune cells, and the inhibition of viral replication.

Clinical significance

IL-28 has been implicated in several diseases, including Hepatitis C, Multiple sclerosis, and certain types of cancer. In Hepatitis C, IL-28 is thought to play a role in the body's response to the virus. In Multiple sclerosis, IL-28 may be involved in the inflammatory response that damages the nerves. In cancer, IL-28 may play a role in the immune response against the tumor.

Research

Research is ongoing to better understand the role of IL-28 in the immune response and its potential as a therapeutic target. Some studies have suggested that IL-28 may be a potential biomarker for certain diseases, such as Hepatitis C and Multiple sclerosis. Other research is focused on developing drugs that can modulate the activity of IL-28, with the aim of improving the treatment of diseases in which IL-28 is involved.

See also

• Interleukin
• Cytokine
• Interferon
• Hepatitis C
• Multiple sclerosis

Interleukin-28 Resources
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