Intermesenteric plexus

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Intermesenteric Plexus

The Intermesenteric Plexus (also known as Auerbach's plexus) is a significant part of the enteric nervous system that provides innervation to the gastrointestinal tract. It is located between the muscular layers of the gut, specifically between the longitudinal and circular layers of the muscularis externa.

Etymology[edit | edit source]

The term "Intermesenteric Plexus" is derived from the Latin words "inter" meaning between, "mesenteric" referring to the mesentery, and "plexus" meaning a network. The term "Auerbach's plexus" is named after Leopold Auerbach, a German anatomist who first described it in 1862.

Structure[edit | edit source]

The Intermesenteric Plexus is a large network of nerve fibers and neuron cell bodies (ganglia) that are situated between the longitudinal and circular muscle layers of the gut wall. It extends from the esophagus to the anus, providing a continuous supply of innervation to the entire length of the gut.

Function[edit | edit source]

The primary function of the Intermesenteric Plexus is to control the gastrointestinal motility. It does this by coordinating the contraction and relaxation of the smooth muscle layers of the gut wall. This allows for the propulsion of food and waste materials along the length of the gut.

Clinical Significance[edit | edit source]

Damage or dysfunction of the Intermesenteric Plexus can lead to a variety of gastrointestinal disorders, including achalasia, gastroparesis, and Hirschsprung's disease. These conditions are characterized by impaired motility of the gut, leading to symptoms such as difficulty swallowing, nausea, vomiting, and constipation.

See Also[edit | edit source]

References[edit | edit source]

Intermesenteric plexus Resources
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Contributors: Prab R. Tumpati, MD