Irritation

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This person has irritated skin for using a product that she is allergic to.

Tissue irritation is a physiological response manifested by the onset of inflammation, pain, or other discomforting reactions due to various stimuli, including allergies, cellular damage, or external irritants. It can significantly impact different tissues in the body, with the skin and eyes being commonly affected.

Urticaria near navel
Hives on back
Urticaria arm

Definition[edit | edit source]

In the context of biology, irritation refers to an unpleasant sensation, often characterized by inflammation or pain. It's typically a defensive response to harmful stimuli, aiming to remove or minimize the adverse effect of the irritant.

Causes[edit | edit source]

Irritation can be triggered by several factors:

  • Physical irritants: Including heat, cold, radiation, or physical trauma.
  • Chemical irritants: Such as detergents, solvents, or other chemicals that come in contact with the skin.
  • Biological irritants: Like pathogens, insect bites, or plant toxins.
  • Allergies: Hypersensitive reactions of the immune system to specific substances.
  • Cellular damage: Damage at the cellular level can lead to inflammation and irritation.

Common Symptoms[edit | edit source]

  • Redness: Often one of the earliest signs of irritation.
  • Swelling: Caused by an accumulation of fluid in the tissues.
  • Pain: Varying levels of discomfort or painful sensations.
  • Heat: The affected area might feel warm to the touch.
  • Itching: An unpleasant sensation leading to the desire to scratch.

Prevention and Treatment[edit | edit source]

Avoiding known irritants is the primary preventive measure. However, once irritation occurs:

  • Cooling: Using cold compresses can reduce inflammation.
  • Topical creams: Creams or ointments containing corticosteroids or other anti-inflammatory agents.
  • Antihistamines: Useful in cases where the irritation is due to an allergic reaction.
  • Moisturizing: Helps soothe the skin and prevent further irritation.
  • Avoidance: Keeping away from the irritant or allergen causing the issue.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD