Isotopes of iodine

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Isotopes of Iodine refer to the different atomic forms of the chemical element iodine. Each isotope of iodine contains 53 protons in its nucleus but differs in the number of neutrons. Iodine's atomic number is 53, and its chemical symbol is I. The isotopes of iodine range from having very few neutrons to having many more than the stable isotopes. Among these, only one is stable: Iodine-127 (127I), which is also the only naturally occurring isotope of iodine.

Stable and Radioactive Isotopes[edit | edit source]

The most significant isotope of iodine for biological systems and medical applications is 127I, due to its stability and natural abundance. However, several radioactive isotopes of iodine have critical applications in medicine and industry, notably 123I, 124I, 125I, and 131I.

Radioactive Isotopes[edit | edit source]

  • 123I is used in nuclear medicine for imaging and diagnostic purposes, particularly in thyroid scans.
  • 124I is used in Positron Emission Tomography (PET) scans, offering detailed images for diagnostic purposes.
  • 125I is used in radiotherapy for treating certain types of cancer, as well as in various laboratory assays.
  • 131I is well-known for its use in treating thyroid cancer and hyperthyroidism, as it concentrates in the thyroid gland and destroys thyroid tissue with its beta emissions.

Decay and Half-Life[edit | edit source]

Each radioactive isotope of iodine has a specific half-life, the time it takes for half of the isotope to decay. For example, 131I has a half-life of about 8 days, making it suitable for medical treatments as it decays relatively quickly, minimizing radiation exposure to the patient.

Production[edit | edit source]

Radioactive isotopes of iodine are typically produced in nuclear reactors or cyclotrons by bombarding a target, usually made of xenon or tellurium, with neutrons or protons.

Applications[edit | edit source]

Beyond medical applications, isotopes of iodine have uses in environmental science, such as tracking animal migration and studying ocean circulation patterns through the analysis of iodine isotopes in soil and water samples.

Safety and Environmental Concerns[edit | edit source]

While isotopes like 131I are invaluable in medicine, they also pose safety and environmental concerns. For instance, 131I released into the environment as a result of nuclear accidents or tests can be absorbed by the thyroid gland, potentially causing thyroid cancer. Therefore, handling and disposal of iodine isotopes, especially the radioactive ones, require strict safety protocols to protect both human health and the environment.

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Contributors: Prab R. Tumpati, MD