JWH-091

JWH-091 is a synthetic cannabinoid from the naphthoylindole family. It acts as a partial agonist at both the CB₁ and CB₂ cannabinoid receptors, with a relatively low affinity for the CB₁ receptor.

Chemistry

JWH-091 is a member of the naphthoylindole family of synthetic cannabinoids. It is structurally related to other synthetic cannabinoids such as JWH-018 and JWH-073. The compound is named after the initials of its developer, John W. Huffman, a chemist at Clemson University.

Pharmacology

JWH-091 acts as a partial agonist at both the CB₁ and CB₂ cannabinoid receptors. It has a relatively low affinity for the CB₁ receptor, which is primarily found in the brain and is responsible for the psychoactive effects of cannabis. The CB₂ receptor, on the other hand, is primarily found in the immune system.

Effects

The effects of JWH-091 are not well-studied. However, due to its action at the cannabinoid receptors, it is likely to produce effects similar to those of cannabis, including euphoria, relaxation, and altered perception. The potential for adverse effects, such as anxiety, paranoia, and psychosis, is also present.

Legal Status

The legal status of JWH-091 varies by country. In many places, it is considered a controlled substance due to its similarity to cannabis.

See Also

• Synthetic cannabinoids
• Cannabinoid receptor
• JWH-018
• JWH-073

JWH-091 Resources
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