KIF27

Ideogram human chromosome 9

== KIF27 ==

KIF27 is a gene that encodes a protein involved in cellular functions. It is located on chromosome 19 in humans.

Function

The KIF27 protein belongs to the kinesin superfamily of motor proteins. It plays a role in intracellular transport and cellular organization. Studies have shown that KIF27 is important for the proper functioning of cilia, which are hair-like structures on the surface of cells involved in various physiological processes.

Structure

The KIF27 gene consists of several exons that encode a protein with motor domains characteristic of kinesins. These motor domains enable KIF27 to move along microtubules within the cell.

Clinical Significance

Mutations in the KIF27 gene have been associated with certain genetic disorders affecting cilia function. These disorders can lead to a range of symptoms, including respiratory issues, infertility, and developmental abnormalities.

Research

Research on KIF27 continues to uncover its role in cellular processes and its potential as a therapeutic target for ciliopathies and other related conditions.