Katherine A. Hoadley

American cancer researcher

Katherine A. Hoadley

Katherine A. Hoadley is an American cancer researcher and professor known for her work in the field of cancer genomics. She is a faculty member at the University of North Carolina at Chapel Hill and a prominent figure in the study of breast cancer and other types of cancer through genomic analysis.

Education and Early Career

Katherine Hoadley completed her undergraduate studies in biology at the University of North Carolina at Chapel Hill. She then pursued her doctoral studies in genetics and molecular biology, earning a Ph.D. from the same institution. Her early research focused on the genetic underpinnings of cancer, which laid the foundation for her future work in cancer genomics.

Research and Contributions

Hoadley is best known for her contributions to the Cancer Genome Atlas (TCGA) project, a comprehensive effort to map the genomic changes in various types of cancer. Her work has been instrumental in classifying cancers based on their molecular characteristics rather than their tissue of origin, which has significant implications for personalized medicine.

Breast Cancer Genomics

One of Hoadley's major research areas is breast cancer. She has been involved in studies that categorize breast cancer into distinct molecular subtypes, which helps in understanding the disease's heterogeneity and in developing targeted therapies. Her research has shown that breast cancer can be divided into several subtypes, each with unique genetic and molecular profiles.

Pan-Cancer Analysis

Hoadley has also contributed to pan-cancer analyses, which compare genomic data across different types of cancer. This work has revealed commonalities and differences in the genetic alterations that drive various cancers, providing insights into potential therapeutic targets and strategies for treatment.

Academic and Professional Roles

At the University of North Carolina, Hoadley holds a position as an associate professor in the Department of Genetics. She is also a member of the Lineberger Comprehensive Cancer Center, where she collaborates with other researchers to advance the understanding of cancer biology and treatment.

Awards and Recognition

Throughout her career, Hoadley has received numerous awards and honors for her contributions to cancer research. Her work is widely published in leading scientific journals, and she is frequently invited to speak at national and international conferences on cancer genomics.

Related Pages

• Cancer Genome Atlas
• Breast cancer
• Genomics
• Personalized medicine