Keratin associated protein 5-6
Keratin associated protein 5-6
Keratin associated protein 5-6, also known as KRTAP5-6, is a type of protein that is associated with keratin in the human body. It is encoded by the KRTAP5-6 gene located on chromosome 21. This protein plays a role in the structure and function of hair and nails.
Structure[edit | edit source]
Keratin associated protein 5-6 is a member of the keratin-associated protein family, which includes various proteins that interact with keratin to form the structure of hair and nails. The specific function of KRTAP5-6 is to provide stability and strength to the hair shaft.
Function[edit | edit source]
The main function of Keratin associated protein 5-6 is to contribute to the structural integrity of hair fibers. It interacts with keratin proteins to form a strong network that gives hair its strength and resilience. Mutations in the KRTAP5-6 gene can lead to hair disorders and abnormalities.
Clinical Significance[edit | edit source]
Research has shown that mutations in the KRTAP5-6 gene can result in various hair disorders, such as alopecia and brittle hair syndrome. Understanding the role of this protein in hair structure can help in the development of treatments for these conditions.
References[edit | edit source]
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