L-759,633
L-759,633 is a drug that acts as a potent and selective agonist for the cannabinoid receptor CB2, with reasonable selectivity over the psychoactive CB1 receptor, though with some variation between species. It has analgesic effects in animal studies, particularly for "atypical" pain conditions like chronic and neuropathic pain, where many other analgesics are ineffective.
Pharmacology[edit | edit source]
L-759,633 is a cannabinoid drug that has been developed for its potential therapeutic applications. It is a potent and selective agonist for the CB2 receptor, which is primarily found in the peripheral tissues of the body, rather than in the brain. This means that L-759,633 can produce its therapeutic effects without causing the psychoactive effects that are associated with activation of the CB1 receptor.
Therapeutic Applications[edit | edit source]
The primary potential therapeutic application of L-759,633 is as an analgesic. It has been found to be effective in animal studies for treating various types of pain, including chronic pain and neuropathic pain. These are types of pain that are often difficult to treat with other analgesics, so L-759,633 could potentially fill an important gap in the treatment options available for these conditions.
Side Effects[edit | edit source]
As a CB2 receptor agonist, L-759,633 is not expected to produce the psychoactive side effects that are associated with CB1 receptor agonists. However, the potential side effects of L-759,633 have not been fully studied, so it is not yet known what side effects it might have.
Research[edit | edit source]
Research into the potential therapeutic applications of L-759,633 is ongoing. It is hoped that this research will lead to the development of new treatments for conditions that are currently difficult to treat with existing analgesics.
| L-759,633 Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
