LNCaP
LNCaP is a human cell line commonly used in cancer research, particularly in the study of prostate cancer. This cell line was derived from a lymph node metastasis of a human prostatic adenocarcinoma.
Characteristics[edit | edit source]
LNCaP cells are known for their sensitivity to androgens, which are hormones that play a crucial role in the development and maintenance of male characteristics. This makes them an important model for studying androgen receptor signaling and the effects of androgen deprivation therapy in prostate cancer.
Applications[edit | edit source]
LNCaP cells are widely used in drug discovery and biomedical research to test the efficacy of new therapeutic agents targeting prostate cancer. They are also used to study the mechanisms of cancer progression and metastasis.
Culture Conditions[edit | edit source]
LNCaP cells are typically cultured in RPMI 1640 medium supplemented with 10% fetal bovine serum (FBS) and maintained at 37°C in a humidified atmosphere containing 5% carbon dioxide.
See Also[edit | edit source]
References[edit | edit source]
External Links[edit | edit source]
- [LNCaP cell line information at ATCC](https://www.atcc.org/products/all/CRL-1740.aspx)
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
