LY-320,135
LY-320,135 is a drug that acts as an antagonist for the cannabinoid receptor CB1. It was developed by the pharmaceutical company Eli Lilly and has been used in scientific research to study the function of the CB1 receptor, particularly in relation to the effects of other drugs that act on this receptor.
Pharmacology[edit | edit source]
LY-320,135 is a CB1 receptor antagonist, which means it blocks the action of cannabinoid drugs at the CB1 receptor. This receptor is found in various parts of the brain and is involved in a wide range of physiological processes, including appetite regulation, pain sensation, mood, and memory.
The CB1 receptor is the primary target of the psychoactive ingredient in cannabis, delta-9-tetrahydrocannabinol (THC). By blocking the action of THC and other cannabinoids at the CB1 receptor, LY-320,135 can prevent or reduce the psychoactive effects of these drugs.
Research Uses[edit | edit source]
LY-320,135 has been used in scientific research to study the function of the CB1 receptor and the effects of drugs that act on this receptor. For example, it has been used to investigate the role of the CB1 receptor in the effects of cannabinoids on appetite and food intake, as well as their effects on pain sensation and mood.
In addition, LY-320,135 has been used to study the potential therapeutic applications of CB1 receptor antagonists. For instance, it has been used in research investigating the potential use of these drugs in the treatment of obesity, as they may help to reduce appetite and food intake.
See Also[edit | edit source]
References[edit | edit source]
 | This pharmacology-related article is a stub. You can help WikiMD by expanding it. |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
