LY-404187
LY-404187 is a potent and selective AMPAR potentiator. It has been shown to have potential use in the treatment of schizophrenia and related conditions, and has been investigated for its nootropic effects.
Pharmacology[edit | edit source]
LY-404187 is a potent and selective AMPA receptor potentiator, which means it enhances the activity of the AMPA receptor. The AMPA receptor is one of the three main types of ionotropic glutamate receptors, and it plays a key role in the fast synaptic transmission of excitatory signals in the brain.
LY-404187 has been shown to have potential use in the treatment of schizophrenia and related conditions. Schizophrenia is a chronic and severe mental disorder that affects how a person thinks, feels, and behaves. It is characterized by distortions in thinking, perception, emotions, language, sense of self, and behavior.
In addition to its potential use in the treatment of schizophrenia, LY-404187 has also been investigated for its nootropic effects. Nootropics, also known as "smart drugs", are substances that can improve cognitive function, particularly executive functions, memory, creativity, or motivation, in healthy individuals.
Clinical Trials[edit | edit source]
LY-404187 has undergone clinical trials to evaluate its safety and efficacy in the treatment of schizophrenia. The results of these trials have shown that LY-404187 is safe and well-tolerated, and it has demonstrated potential efficacy in improving the cognitive deficits associated with schizophrenia.
See Also[edit | edit source]
References[edit | edit source]
| LY-404187 Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
