Laurin-Sandrow syndrome
Alternate names[edit | edit source]
Fibula ulna duplication tibia radius absence; Sandrow syndrome; Mirror hands and feet with nasal defects; Tetramelic mirror-image polydactyly; Laurin Sandrow syndrome
Definition[edit | edit source]
Laurin-Sandrow syndrome (LSS) is characterised by complete polysyndactyly of the hands, mirror feet and nose anomalies (hypoplasia of the nasal alae and short columella), often associated with ulnar and/or fibular duplication (and sometimes tibial agenesis). It has been described in less than 20 cases. Some cases with the same clinical signs but without nasal defects have also been reported, and may represent the same entity. The etiology of LSS is unknown. Different modes of inheritance have been suggested.
NIH genetic and rare disease info[edit source]
Laurin-Sandrow syndrome is a rare disease.
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