Leptomeninges

Leptomeninges is a collective term referring to the two innermost layers of the meninges, the pia mater and arachnoid mater. These layers cover the brain and spinal cord, providing protection and support. The leptomeninges are involved in various physiological processes, including the production and circulation of cerebrospinal fluid (CSF). They also play a role in certain pathological conditions, such as meningitis and leptomeningeal carcinomatosis.

Structure

The leptomeninges consist of two layers: the pia mater and the arachnoid mater. The pia mater is the innermost layer, directly adhering to the surface of the brain and spinal cord. It is a thin, delicate membrane composed of fibrous tissue and small blood vessels. The arachnoid mater is the middle layer of the meninges, lying between the pia mater and the outermost layer, the dura mater. It is a thin, avascular membrane composed of fibrous and elastic tissue.

Function

The leptomeninges play a crucial role in the production and circulation of CSF. The CSF is produced by the choroid plexus, located within the ventricles of the brain, and circulates through the subarachnoid space, a gap between the pia mater and arachnoid mater filled with CSF. The leptomeninges also provide physical protection and support to the brain and spinal cord.

Clinical significance

Inflammation of the leptomeninges, known as meningitis, can occur due to various causes, including bacterial, viral, and fungal infections. Leptomeningeal carcinomatosis, a rare complication of cancer, occurs when malignant cells infiltrate the leptomeninges.

See also

• Meninges
• Pia mater
• Arachnoid mater
• Cerebrospinal fluid
• Meningitis
• Leptomeningeal carcinomatosis

Leptomeninges Resources
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