Levomefolate calcium

Levomefolate calcium is a biologically active form of folic acid, also known as L-methylfolate. It is used in the treatment of major depressive disorder and folate deficiency. It is also used in dietary supplements and fortified foods.

Chemistry

Levomefolate calcium is a salt form of L-methylfolate, an active form of folic acid. It is a water-soluble vitamin that is part of the B vitamin group. It is a cofactor in many biological reactions, including the synthesis of DNA and amino acids.

Pharmacology

Levomefolate calcium is used in the treatment of major depressive disorder and folate deficiency. It is also used in dietary supplements and fortified foods. It is absorbed in the small intestine and transported to the liver where it is converted into its active form, 5-methyltetrahydrofolate (5-MTHF). 5-MTHF is then distributed throughout the body where it is used in various biological reactions.

Clinical use

Levomefolate calcium is used in the treatment of major depressive disorder. It is also used to treat folate deficiency, which can occur in individuals who do not consume enough folic acid in their diet, or in individuals who have a genetic mutation that prevents them from converting folic acid into its active form.

Side effects

Common side effects of levomefolate calcium include nausea, stomach upset, and skin rash. In rare cases, it can cause serious allergic reactions.

See also

• Folic acid
• Major depressive disorder
• Folate deficiency

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