Lipid-lowering agent

From WikiMD's Wellness Encyclopedia

Lipid-lowering agents are a group of medications used to treat high levels of lipids, such as cholesterol and triglycerides, in the blood. These agents work by reducing the production of lipids in the liver or by increasing the removal of lipids from the blood.

Types of Lipid-lowering agents[edit | edit source]

There are several types of lipid-lowering agents, including:

  • Statins: These are the most commonly used lipid-lowering agents. They work by inhibiting the enzyme HMG-CoA reductase, which is involved in the production of cholesterol in the liver.
  • Fibrates: These agents work by reducing the production of triglycerides and increasing the uptake of triglycerides from the blood.
  • Niacin: This is a type of B vitamin that can reduce LDL cholesterol and increase HDL cholesterol.
  • Bile acid sequestrants: These agents work by binding to bile acids in the intestine, preventing their reabsorption and thereby reducing the level of cholesterol in the blood.
  • Ezetimibe: This medication works by reducing the absorption of cholesterol from the diet.

Uses[edit | edit source]

Lipid-lowering agents are used to treat high levels of lipids in the blood, a condition known as hyperlipidemia. They are also used to reduce the risk of cardiovascular disease, including heart attack and stroke, in people with high cholesterol levels.

Side Effects[edit | edit source]

Like all medications, lipid-lowering agents can cause side effects. These can include muscle pain, liver damage, increased blood sugar levels, and neurological side effects like memory loss or confusion. It's important to discuss these potential side effects with your healthcare provider before starting treatment.

See Also[edit | edit source]

Lipid-lowering agent Resources
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Contributors: Prab R. Tumpati, MD