Lipofuscin

From WikiMD's Wellness Encyclopedia

Lipofuscin is a type of lipid-containing residue that accumulates in various organs in the human body over time. It is often referred to as an "aging pigment," as its levels increase with age. Lipofuscin is composed of various substances, including lipids, proteins, and metals.

Composition[edit | edit source]

Lipofuscin is a complex mixture of substances, including lipids, proteins, and metals. The exact composition can vary depending on the tissue and age of the individual. However, it is generally composed of approximately 30% protein, 30% lipid, and 40% carbohydrates.

Accumulation[edit | edit source]

Lipofuscin accumulates in the lysosomes of cells over time. This is due to the fact that it is resistant to enzymatic degradation. The accumulation of lipofuscin can lead to a decrease in cellular function and can contribute to the aging process.

Effects[edit | edit source]

The accumulation of lipofuscin can have various effects on the body. It can lead to a decrease in cellular function, which can contribute to the aging process. In addition, it can also lead to various diseases, including Alzheimer's disease, Parkinson's disease, and macular degeneration.

Research[edit | edit source]

Research is currently being conducted to better understand the role of lipofuscin in the aging process and disease development. This includes studies on the composition of lipofuscin, its effects on cellular function, and potential ways to prevent its accumulation.

See also[edit | edit source]

Lipofuscin Resources
Wikipedia
WikiMD
Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD

Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD

WikiMD's Wellness Encyclopedia

Let Food Be Thy Medicine
Medicine Thy Food - Hippocrates

Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.

Contributors: Prab R. Tumpati, MD