List of MeSH codes (D03)

List of MeSH codes (D03) refers to a comprehensive categorization within the Medical Subject Headings (MeSH) system, specifically focusing on the section designated as D03, which encompasses chemicals and drugs. MeSH is a hierarchical controlled vocabulary used for indexing, cataloging, and searching for biomedical and health-related information. The D03 category is subdivided into various subcategories that classify drugs and chemical substances based on their chemical structure, pharmacological properties, and therapeutic uses.

Overview

The D03 category of MeSH codes is integral for researchers, healthcare professionals, and librarians for organizing and retrieving pharmaceutical and chemical literature. This categorization aids in the precise identification of substances and their effects, facilitating a more efficient search process in databases such as PubMed and the MEDLINE indexing system.

Structure

The structure of the D03 category in the MeSH hierarchy includes several subcategories that cover a wide range of chemical compounds, from organic chemicals to complex biopolymers. Each subcategory is identified by a unique MeSH code and includes specific groups of chemicals or drugs that share common characteristics. These subcategories are further divided into more specific groups, allowing for detailed classification.

Organic Chemicals (D03.438)

This subcategory includes carbon-containing compounds, except for certain simple ones (like carbonates, carbides, etc.). It encompasses a vast array of substances, including hydrocarbons, alcohols, aldehydes, and acids.

Heterocyclic Compounds (D03.633)

Heterocyclic compounds are chemicals that contain a ring structure composed of at least two different types of atoms. This subcategory is divided based on the number of atoms in the ring and the atoms involved, such as pyridines, pyrimidines, and indoles.

Polycyclic Compounds (D03.438.759)

These are compounds that contain multiple cyclic structures. They include important biologically active molecules like steroids, terpenes, and certain types of aromatic hydrocarbons.

Macromolecular Substances (D03.633.100)

This group includes large molecules, often referred to as polymers, which are made up of repeating subunits. Examples include proteins, nucleic acids, and polysaccharides.

Hormones, Hormone Substitutes, and Hormone Antagonists (D03.633.100.759.758)

This subcategory includes substances that act similarly to hormones, those that can replace hormones in case of deficiency, and agents that can inhibit the action of hormones.

Enzymes and Coenzymes (D03.633.100.759.646)

Enzymes are biological catalysts that speed up chemical reactions in the body, while coenzymes are small organic molecules that assist enzymes in their catalytic activity.

Carbohydrates (D03.066)

Carbohydrates are essential nutrients that serve as a major energy source. This subcategory includes simple sugars, complex polysaccharides, and dietary fiber.

Importance

The classification of chemicals and drugs into the MeSH D03 category and its subcategories plays a crucial role in the organization of biomedical information. It enables researchers and healthcare professionals to efficiently locate and access specific information on chemical substances and their biological effects, supporting evidence-based practice and scientific discovery.