List of Schedule III drugs (US)

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List of Schedule III Drugs (US)

The List of Schedule III Drugs in the United States encompasses a category of controlled substances as defined by the Controlled Substances Act (CSA) of 1970. Schedule III drugs are considered to have a moderate to low potential for physical and psychological dependence compared to substances listed in Schedules I and II. The Drug Enforcement Administration (DEA) is responsible for the classification of drugs and enforcement of regulations related to their manufacture, distribution, and use.

Classification Criteria[edit | edit source]

Schedule III drugs are characterized by the following criteria:

  • The substance has a potential for abuse less than the substances in Schedules I and II.
  • The substance has a currently accepted medical use in treatment in the United States.
  • Abuse of the substance may lead to moderate or low physical dependence or high psychological dependence.

Examples of Schedule III Drugs[edit | edit source]

This list includes, but is not limited to, the following substances:

  • Anabolic steroids - Synthetic substances related to male sex hormones, used medically to treat conditions like hormone disorders and muscle loss.
  • Ketamine - A medication primarily used for starting and maintaining anesthesia, known for its dissociative properties.
  • Buprenorphine - Often used in the treatment of opioid addiction, as well as for pain management.
  • Testosterone - A naturally occurring male hormone used in replacement therapy and to treat various health conditions.

Regulations and Restrictions[edit | edit source]

Schedule III drugs are subject to federal and state regulations, which include:

  • Requirement for a written or electronic prescription with a signature from a licensed practitioner.
  • Prescriptions may be refilled up to five times within six months after the date of issue.
  • Manufacturers, distributors, and dispensers of these substances must register with the DEA and comply with record-keeping and inventory requirements.

Legal Implications[edit | edit source]

The possession, distribution, or manufacture of Schedule III drugs without a valid medical prescription or license can result in legal penalties, including fines and imprisonment. The severity of these penalties can vary depending on the quantity of the substance and the nature of the offense.

Conclusion[edit | edit source]

The classification of drugs into Schedule III is part of the United States' effort to balance the need for access to medications for legitimate medical purposes with the need to prevent abuse and addiction. As scientific understanding and societal norms evolve, the list of Schedule III drugs may be updated to reflect new evidence regarding the substances' abuse potential and medical utility.

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Contributors: Prab R. Tumpati, MD