List of steroid metabolism modulators

Steroid metabolism modulators are a class of drugs that interact with the steroid metabolism in the body. They can either inhibit or enhance the metabolic processes that steroids undergo, thereby affecting the overall levels and effects of steroids in the body. This article provides a list of some of the most commonly used steroid metabolism modulators.

Steroid Metabolism

Steroid metabolism is a complex process that involves the conversion of cholesterol into various types of steroids in the body. This process is regulated by a series of enzymes, which can be influenced by certain drugs known as steroid metabolism modulators.

List of Steroid Metabolism Modulators

Aromatase Inhibitors

Aromatase inhibitors are a class of drugs that inhibit the enzyme aromatase, which is responsible for the conversion of androgens into estrogens. Examples of aromatase inhibitors include:

• Anastrozole
• Letrozole
• Exemestane

5-Alpha-Reductase Inhibitors

5-alpha-reductase inhibitors are a class of drugs that inhibit the enzyme 5-alpha-reductase, which is responsible for the conversion of testosterone into dihydrotestosterone (DHT). Examples of 5-alpha-reductase inhibitors include:

• Finasteride
• Dutasteride

Steroid Sulfatase Inhibitors

Steroid sulfatase inhibitors are a class of drugs that inhibit the enzyme steroid sulfatase, which is responsible for the conversion of steroid sulfates into free steroids. Examples of steroid sulfatase inhibitors include:

• Irosustat
• Estrone sulfamate

See Also

• Steroidogenesis inhibitor
• Steroidogenic enzyme

References

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