Live attenuated vaccine
It is a vaccine with live pathogen that has been attenuated to become less virulent in order to produce an active but subclinical infection.
Benefits[edit | edit source]
- Because these vaccines are so similar to the natural infection that they help prevent, they create a stronger and longer-lasting immune response.
- The other benefit is that just 1 or 2 doses of most live vaccines can give you a lifetime of protection against a germ and the disease it causes.
Limitations[edit | edit source]
But live vaccines also have some limitations. Because they contain a small amount of the weakened live virus, some people should talk to their health care provider before receiving them, such as people with weakened immune systems, long-term health problems, or people who’ve had an organ transplant.
Refrigeration requirements[edit | edit source]
They need to be kept cool, so they don’t travel well. That means they can’t be used in countries or areas with limited access to refrigerators.
List of live attenuated vaccines[edit | edit source]
List of live attenuated bacterial vaccines
- Anthrax vaccine
- Cholera vaccine
- Plague vaccine
- Salmonella vaccine
- Tuberculosis vaccine
- Typhoid vaccine
List of live attenuated viral vaccines
- Japanese encephalitis vaccine
- Measles vaccine
- Mumps vaccine
- MMR vaccine
- Polio vaccine
- Rotavirus vaccine
- Rubella vaccine
- Smallpox vaccine
- Varicella vaccine
- Yellow fever vaccine
- Shingles vaccine
- Live attenuated influenza vaccine (LAIV)
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Contributors: Prab R. Tumpati, MD