Major facilitator superfamily domain-containing protein 9

Ideogram human chromosome 2

Major facilitator superfamily domain-containing protein 9

The Major facilitator superfamily domain-containing protein 9 (MFS9) is a protein encoded by the MFS9 gene in humans. It belongs to the major facilitator superfamily (MFS) of transport proteins, which are involved in the transport of various substrates across cell membranes.

Structure

MFS9 is composed of approximately 400 amino acids and contains 12 transmembrane domains. These transmembrane domains play a crucial role in the transport function of the protein by forming a channel through which substrates can pass.

Function

MFS9 is primarily involved in the transport of small molecules, such as sugars, amino acids, and ions, across cell membranes. It acts as a facilitator by aiding in the movement of these molecules from areas of high concentration to areas of low concentration.

Clinical Significance

Mutations in the MFS9 gene have been associated with certain diseases and disorders, including metabolic disorders and drug resistance. Understanding the function of MFS9 and its role in cellular transport processes is important for developing targeted therapies for these conditions.

References

1. Smith A, Jones B. (Year). Title of the Paper. Journal Name. Volume(Issue):Page numbers. 2. Lastname F. (Year). Title of the Book. Publisher.