Manoalide
Manoalide is a natural compound that is derived from the marine sponge Luffariella variabilis. It is known for its anti-inflammatory properties and has been studied for its potential use in the treatment of various diseases.
History[edit | edit source]
Manoalide was first isolated in 1983 from the marine sponge Luffariella variabilis. The compound was named after Manoa, the Hawaiian word for "vast", in reference to the vast potential of the marine environment as a source of new drugs.
Structure and Properties[edit | edit source]
Manoalide is a sesterterpenoid, a class of terpenes that contain 25 carbon atoms. It has a complex structure that includes a lactone ring and several hydroxyl groups. The compound is highly lipophilic, which allows it to easily cross cell membranes.
Biological Activity[edit | edit source]
Manoalide has a variety of biological activities. It is best known for its anti-inflammatory effects, which are believed to be due to its ability to inhibit the enzyme phospholipase A2. This enzyme is involved in the production of inflammatory mediators, so inhibiting it can reduce inflammation.
In addition to its anti-inflammatory effects, manoalide has also been found to have analgesic, antifungal, and antiviral activities. It has been studied for its potential use in the treatment of diseases such as arthritis, cancer, and viral infections.
Research and Clinical Trials[edit | edit source]
While manoalide has shown promise in laboratory studies, it has not yet been approved for use in humans. Clinical trials are needed to determine the safety and efficacy of this compound in patients.
See Also[edit | edit source]
References[edit | edit source]
| Manoalide Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
