Oxamniquine
(Redirected from Mansil)
Oxamniquine is an anthelmintic drug that was developed in the 1960s by Pfizer. It is primarily used in the treatment of schistosomiasis, a disease caused by parasitic worms.
History[edit | edit source]
Oxamniquine was developed by Pfizer in the 1960s as a response to the global health issue of schistosomiasis. The drug was specifically designed to treat infections caused by Schistosoma mansoni, one of the main species of schistosome that infects humans.
Pharmacology[edit | edit source]
Oxamniquine works by causing paralysis in the schistosome worm, preventing it from attaching to blood vessels and causing damage. The drug is metabolized in the liver and excreted in the urine.
Clinical use[edit | edit source]
Oxamniquine is used in the treatment of schistosomiasis caused by S. mansoni. It is administered orally, usually in a single dose. The drug is generally well-tolerated, with side effects including dizziness, headache, and gastrointestinal symptoms.
Resistance[edit | edit source]
Resistance to oxamniquine has been reported in some populations of S. mansoni. This has led to the development of new drugs, such as praziquantel, which is now the first-line treatment for schistosomiasis.
See also[edit | edit source]
 | This pharmacology-related article is a stub. You can help WikiMD by expanding it. |
 | This medical article is a stub. You can help WikiMD by expanding it. |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
