Marcin Kortylewski

Polish-American cancer researcher

Marcin Kortylewski in 2022

Marcin Kortylewski is a prominent Polish-American cancer researcher known for his work in the field of immuno-oncology. He is a professor at the City of Hope National Medical Center in Duarte, California, where he leads a research team focused on understanding the role of the immune system in cancer progression and therapy.

Early Life and Education

Marcin Kortylewski was born in Poland. He pursued his early education in Poland before moving to the United States for advanced studies. Kortylewski earned his Ph.D. in molecular biology, where he developed a keen interest in the mechanisms of cancer and the potential for immunotherapy to treat it.

Research and Career

Kortylewski's research primarily focuses on the signal transducer and activator of transcription 3 (STAT3) pathway, which plays a critical role in the immune evasion of cancer cells. His work has been instrumental in understanding how cancer cells manipulate the immune system to avoid detection and destruction.

At the City of Hope, Kortylewski's laboratory investigates the molecular mechanisms by which STAT3 contributes to tumor immune evasion and resistance to therapy. His team is developing novel therapeutic strategies to inhibit STAT3 signaling in tumor microenvironments, aiming to enhance the efficacy of existing cancer treatments.

Contributions to Immuno-Oncology

Kortylewski has made significant contributions to the field of immuno-oncology, particularly in the development of RNA-based therapies targeting the STAT3 pathway. His research has led to the identification of new drug targets and the development of innovative therapeutic approaches that are currently being tested in preclinical and clinical settings.

Awards and Recognition

Throughout his career, Kortylewski has received numerous awards and honors for his contributions to cancer research. He is widely published in leading scientific journals and is a sought-after speaker at international conferences on cancer and immunology.

Personal Life

Marcin Kortylewski is married and has children. He is known for his dedication to mentoring young scientists and fostering a collaborative research environment.

Related Pages

• Immuno-oncology
• Signal transducer and activator of transcription 3
• City of Hope National Medical Center
• Cancer immunotherapy