Meradimate
Meradimate is a chemical compound used in the field of pharmaceuticals. It is a derivative of benzodiazepine, a class of drugs primarily used for treating anxiety, but they also are effective in treating several other conditions.
Chemical Structure[edit | edit source]
Meradimate is a benzodiazepine derivative with the chemical formula C16H12Cl2N2O. It has a molecular weight of 325.18 g/mol. The compound is composed of two chlorine atoms, one nitrogen atom, and one oxygen atom.
Pharmacology[edit | edit source]
Meradimate acts on the central nervous system (CNS) and enhances the effect of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABA_A receptor, resulting in sedative, sleep-inducing (hypnotic), anxiolytic, anticonvulsant, and muscle relaxant properties.
Medical Uses[edit | edit source]
Meradimate is primarily used in the treatment of anxiety disorders, insomnia, and seizure disorders. It is also used as a premedication for inducing sedation, anxiolysis, or amnesia before certain medical procedures.
Side Effects[edit | edit source]
Like other benzodiazepines, Meradimate can cause physical dependence and addiction. Other side effects include drowsiness, dizziness, and loss of coordination. Long-term use can lead to tolerance, dependence, and withdrawal symptoms on abrupt discontinuation.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD