Meso-Hexestrol

Meso-Hexestrol is a synthetic, nonsteroidal estrogen that was never marketed. It is part of the hexestrol family of compounds which also includes diethylstilbestrol and dienestrol. Meso-Hexestrol is a stereoisomer of hexestrol, specifically, it is the (3R,4R)-stereoisomer.

Chemistry

Meso-Hexestrol, also known as (3R,4R)-hexestrol, is a synthetic compound of the hexestrol family. It is a nonsteroidal estrogen, meaning it is not derived from natural sources and does not have a steroidal structure. It is a stereoisomer of hexestrol, which means it has the same molecular formula but a different spatial arrangement of atoms.

Pharmacology

As a nonsteroidal estrogen, Meso-Hexestrol has similar effects to other estrogens. It can bind to and activate estrogen receptors, which are found in various tissues throughout the body. This can lead to a range of effects, such as promoting the growth and development of female secondary sexual characteristics, regulating the menstrual cycle, and maintaining pregnancy.

History

Meso-Hexestrol was never marketed, meaning it was not made available for sale or use. The reasons for this are not clear, but may be related to its pharmacological properties, potential side effects, or other factors.

See also

• Diethylstilbestrol
• Dienestrol
• Estrogen
• Hexestrol

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