Methoxetamine

Methoxetamine (MXE, 3-MeO-2'-Oxo-PCE) is a dissociative anesthetic that has been sold as a designer drug. It is a derivative of ketamine that also contains structural features of eticyclidine and 3-MeO-PCP. Methoxetamine is thought to behave as a NMDA receptor antagonist and dopamine reuptake inhibitor, but it has not been formally studied in animals and it lacks a MEDLINE indexed name.

History

Methoxetamine was first synthesized in 2010 by a chemist who was trying to recreate the effects of ketamine for less cost. It was first sold commercially in 2010.

Pharmacology

Methoxetamine is thought to behave as a NMDA receptor antagonist and dopamine reuptake inhibitor, but it has not been formally studied in animals and it lacks a MEDLINE indexed name. It is a derivative of ketamine that also contains structural features of eticyclidine and 3-MeO-PCP.

Effects

The effects of methoxetamine are similar to those of ketamine but typically longer lasting. The drug produces a feeling of detachment from one's physical body and the external world, known as dissociation. Other effects include hallucinations, euphoria, and memory loss.

Legal status

Methoxetamine is a controlled substance in many countries, including the United States, the United Kingdom, and Australia.

See also

• Ketamine
• Phencyclidine
• Dissociative
• Designer drug

Methoxetamine Resources
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