Methyldiazirinol

Methyldiazirinol

Methyldiazirinol is a chemical compound used in the field of pharmacology. It is also known as 3,3'-azobis(6-amino-1,2,4,5-tetrazine), a name derived from its chemical structure.

Chemical Structure and Properties

Methyldiazirinol is a diazirine derivative, which means it contains a three-membered ring of two nitrogen atoms and one carbon atom. The compound is highly reactive due to the strain of the three-membered ring, and it can undergo a variety of chemical reactions.

Methyldiazirinol is a solid at room temperature, and it is soluble in many organic solvents. It has a molar mass of 194.15 g/mol, and its chemical formula is C6H6N8.

Uses and Applications

In pharmacology, methyldiazirinol is used as a photoaffinity label. Photoaffinity labeling is a technique used to study the interaction between a small molecule and its binding site on a protein. The small molecule, in this case methyldiazirinol, is modified to contain a photoreactive group. When the molecule binds to the protein and the complex is exposed to light, the photoreactive group reacts with the protein, covalently attaching the small molecule to the protein. This allows researchers to identify the binding site of the small molecule on the protein.

Methyldiazirinol is also used in the synthesis of other chemical compounds. Its high reactivity makes it a useful building block in organic synthesis.

Safety and Precautions

Due to its high reactivity, methyldiazirinol should be handled with care. It should be stored in a cool, dry place, away from light and heat sources. It should not be ingested, inhaled, or come into contact with skin or eyes. In case of accidental exposure, seek medical attention immediately.

See Also

• Diazirine
• Photoaffinity labeling
• Organic synthesis