Microgyria

Microgyria is a condition characterized by abnormal development of the brain before birth. The surface of the brain normally has many ridges or folds, called gyri. In microgyria, the gyri are unusually small and densely packed.

Causes

The exact cause of microgyria is unknown, but it is thought to be related to disruptions in the normal development of the brain. This can occur due to genetic mutations, infections during pregnancy, premature birth, or lack of oxygen to the brain.

Symptoms

Symptoms of microgyria can vary widely, depending on the severity and location of the abnormalities. They can include developmental delay, intellectual disability, seizures, and problems with movement.

Diagnosis

Microgyria is typically diagnosed through imaging studies of the brain, such as MRI or CT scan. These can show the characteristic small, densely packed gyri. Genetic testing may also be done to identify any underlying genetic mutations.

Treatment

There is no cure for microgyria, but treatment can help manage symptoms. This may include medications to control seizures, physical therapy to help with movement problems, and special education services for those with intellectual disabilities.

See also

• Polymicrogyria
• Lissencephaly
• Cortical dysplasia

References

Microgyria Resources
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