Milan criteria

From WikiMD's Wellnesspedia

Milan criteria is a set of criteria used to determine the suitability of a patient with HCC for liver transplant. The criteria were established in Milan, Italy, hence the name.

History[edit | edit source]

The Milan criteria were first proposed in 1996 by a team of researchers led by Massimo Colombo. The team conducted a study on patients with HCC who underwent liver transplantation and found that those who met the criteria had a significantly better survival rate.

Criteria[edit | edit source]

The Milan criteria include the following:

  • One liver tumor that is 5 cm or smaller in diameter.
  • Up to three liver tumors, none larger than 3 cm.
  • No evidence of cancer spread outside the liver.

Use[edit | edit source]

The Milan criteria are widely used around the world to determine the eligibility of patients with HCC for liver transplantation. They are endorsed by the WHO and the AASLD.

Criticism[edit | edit source]

Some critics argue that the Milan criteria are too restrictive and exclude many patients who could benefit from a liver transplant. In response to this criticism, several alternative criteria have been proposed, including the UCSF criteria and the Up-to-seven criteria.

See also[edit | edit source]


Milan criteria Resources

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