Mini–mental state examination

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A brief 30-point questionnaire test used to screen for cognitive impairment


The Mini–Mental State Examination (MMSE) is a widely used test of cognitive function among the elderly; it includes tests of orientation, attention, memory, language and visual-spatial skills. The MMSE was introduced by Marshall Folstein and colleagues in 1975, and it has since become a standard tool in the assessment of cognitive impairment.

Purpose[edit | edit source]

The MMSE is used to screen for dementia and to estimate the severity and progression of cognitive impairment. It is also used to follow the course of cognitive changes in an individual over time, making it an effective way to document an individual's response to treatment.

Structure[edit | edit source]

The MMSE consists of a series of questions and tests, each of which is scored with a maximum of 30 points. The test is divided into two sections:

Section 1: Orientation and Memory[edit | edit source]

This section assesses the patient's orientation to time and place, as well as their ability to remember and recall information. Questions may include asking the patient to state the current date, their location, and to recall a list of words.

Section 2: Language and Visual-Spatial Skills[edit | edit source]

This section evaluates the patient's language abilities, including naming objects, repeating phrases, and following commands. It also includes a test of visual-spatial skills, such as copying a complex shape.

Interlocking pentagons used in the MMSE

Scoring[edit | edit source]

The MMSE is scored out of 30 points, with higher scores indicating better cognitive function. A score of 24 or higher is generally considered normal, while scores below this threshold may indicate cognitive impairment. The test is not diagnostic, but it can indicate the need for further evaluation.

Limitations[edit | edit source]

While the MMSE is a useful tool for screening cognitive impairment, it has limitations. It may not detect mild cognitive impairment, and it can be influenced by the patient's educational level, cultural background, and language proficiency. Additionally, it may not be sensitive to changes in cognitive function over short periods.

Administration[edit | edit source]

The MMSE is typically administered by a healthcare professional in a clinical setting. It takes about 10 minutes to complete and requires no special equipment. The test is designed to be simple and quick, making it accessible for use in a variety of settings.

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Contributors: Prab R. Tumpati, MD