Molecular cellular cognition

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Molecular Cellular Cognition is a field of neuroscience that combines molecular biology and cellular physiology to understand the mechanisms underlying cognitive functions. This discipline focuses on the study of the molecular and cellular processes that underlie learning, memory, and other cognitive functions.

Overview[edit | edit source]

Molecular biology is a branch of biology that concerns the molecular basis of biological activity between biomolecules in the various systems of a cell. It has a particular focus on the interactions between the different types of DNA, RNA, and proteins and their biosynthesis, as well as the regulation of these interactions.

Cellular physiology is the biological study of the activities that take place in a cell to keep it alive. This includes the chemical and physical functions that are unique to the cells of living organisms.

Cognitive functions refer to a range of high-level brain functions including learning, memory, attention, perception, and decision making.

Molecular Mechanisms in Cognition[edit | edit source]

The molecular mechanisms involved in cognition are complex and involve a variety of cellular components. These include neurons, the primary cells involved in brain function, and glial cells, which provide support and protection for neurons.

Neurotransmitters are chemicals that transmit signals across a synapse from one neuron to another. They play a key role in the transmission of signals in the brain and are crucial for cognitive function.

Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product, usually a protein. Changes in gene expression can affect cognitive function.

Protein kinases are enzymes that modify other proteins by chemically adding phosphate groups to them (phosphorylation). This process is crucial for many cellular processes, including those involved in cognition.

Cellular Mechanisms in Cognition[edit | edit source]

At the cellular level, cognition involves a variety of processes. These include long-term potentiation (LTP), a persistent strengthening of synapses based on recent patterns of activity. LTP is widely considered one of the major cellular mechanisms that underlies learning and memory.

Neuroplasticity, or brain plasticity, refers to the ability of the brain to change throughout an individual's life. This includes changes in neural pathways and synapses due to changes in behavior, environment, neural processes, and bodily injury.

Neurogenesis is the process by which new neurons are formed in the brain. This process is thought to contribute to the formation of new memories and the learning of new skills.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD