Mometasone furoate
Mometasone furoate is a corticosteroid used to treat various skin conditions, allergic reactions, and asthma. It is available in several forms, including topical creams, ointments, lotions, nasal sprays, and inhalers.
Medical Uses[edit | edit source]
Mometasone furoate is primarily used for its anti-inflammatory, antipruritic, and vasoconstrictive properties. It is commonly prescribed for the treatment of:
Topical Application[edit | edit source]
When applied topically, mometasone furoate helps reduce inflammation and itching associated with skin conditions such as eczema and psoriasis. It is available in various formulations, including creams, ointments, and lotions.
Nasal Spray[edit | edit source]
Mometasone furoate nasal spray is used to treat symptoms of allergic rhinitis, such as nasal congestion, sneezing, and runny nose. It is also used to treat nasal polyps.
Inhalation[edit | edit source]
Inhaled mometasone furoate is used for the maintenance treatment of asthma and helps prevent asthma attacks. It is not intended for the relief of acute bronchospasm.
Mechanism of Action[edit | edit source]
Mometasone furoate works by inhibiting the release of substances in the body that cause inflammation. It binds to glucocorticoid receptors, leading to a decrease in the production of inflammatory mediators such as cytokines and prostaglandins.
Side Effects[edit | edit source]
Common side effects of mometasone furoate include:
- Burning sensation
- Itching
- Dryness
- Irritation at the application site
Less common but more serious side effects can include:
Precautions[edit | edit source]
Patients using mometasone furoate should be monitored for signs of adrenal insufficiency, especially if the medication is used over a large surface area or for a prolonged period. It is also important to avoid abrupt discontinuation of the drug to prevent withdrawal symptoms.
Related Pages[edit | edit source]
- Corticosteroid
- Dermatitis
- Psoriasis
- Allergic rhinitis
- Asthma
- Nasal polyps
- Eczema
- Cytokines
- Prostaglandins
- Adrenal insufficiency
- Cushing's syndrome
- Hyperglycemia
- Osteoporosis
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Contributors: Prab R. Tumpati, MD
