Mometasone furoate

Mometasone furoate is a corticosteroid used to treat various skin conditions, allergic reactions, and asthma. It is available in several forms, including topical creams, ointments, lotions, nasal sprays, and inhalers.

Medical Uses

Mometasone furoate is primarily used for its anti-inflammatory, antipruritic, and vasoconstrictive properties. It is commonly prescribed for the treatment of:

• Dermatitis
• Psoriasis
• Allergic rhinitis
• Asthma

Topical Application

When applied topically, mometasone furoate helps reduce inflammation and itching associated with skin conditions such as eczema and psoriasis. It is available in various formulations, including creams, ointments, and lotions.

Nasal Spray

Mometasone furoate nasal spray is used to treat symptoms of allergic rhinitis, such as nasal congestion, sneezing, and runny nose. It is also used to treat nasal polyps.

Inhalation

Inhaled mometasone furoate is used for the maintenance treatment of asthma and helps prevent asthma attacks. It is not intended for the relief of acute bronchospasm.

Mechanism of Action

Mometasone furoate works by inhibiting the release of substances in the body that cause inflammation. It binds to glucocorticoid receptors, leading to a decrease in the production of inflammatory mediators such as cytokines and prostaglandins.

Side Effects

Common side effects of mometasone furoate include:

• Burning sensation
• Itching
• Dryness
• Irritation at the application site

Less common but more serious side effects can include:

• Adrenal suppression
• Cushing's syndrome
• Hyperglycemia
• Osteoporosis

Precautions

Patients using mometasone furoate should be monitored for signs of adrenal insufficiency, especially if the medication is used over a large surface area or for a prolonged period. It is also important to avoid abrupt discontinuation of the drug to prevent withdrawal symptoms.

Related Pages

• Corticosteroid
• Dermatitis
• Psoriasis
• Allergic rhinitis
• Asthma
• Nasal polyps
• Eczema
• Cytokines
• Prostaglandins
• Adrenal insufficiency
• Cushing's syndrome
• Hyperglycemia
• Osteoporosis