Multiple endocrine neoplasia type 2A syndrome
A rare, genetic disorder that affects the endocrine glands and causes a type of thyroid cancer called medullary thyroid cancer, pheochromocytoma, and parathyroid gland cancer.
Benign tumors[edit | edit source]
It may also cause benign (noncancerous) tumors in the parathyroid glands and adrenal glands.
Hormonal disturbance[edit | edit source]
The affected endocrine glands may make high levels of hormones, which can lead to other medical problems such as high blood pressure and kidney stones.
Skin condition[edit | edit source]
An itchy skin condition may also occur.
Genetics[edit | edit source]
Multiple endocrine neoplasia type 2A syndrome is caused by a mutation (change) in a gene called RET.
Other names[edit | edit source]
Also called MEN2A, MEN2A syndrome, multiple endocrine adenomatosis type 2A, and Sipple syndrome.
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This article incorporates public domain material from the U.S. National Cancer Institute document "Dictionary of Cancer Terms".
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Contributors: Prab R. Tumpati, MD
