Myocardial fibrosis

Myocardial fibrosis is a medical condition characterized by the thickening and stiffening of the heart muscle, specifically the myocardium, due to an excessive accumulation of extracellular matrix components, particularly collagen. This condition is often associated with various cardiovascular diseases and can lead to heart failure.

Causes

Myocardial fibrosis can be caused by a variety of factors, including hypertension, myocardial infarction, cardiomyopathy, and aging. It can also be a result of genetic disorders such as Marfan syndrome and Ehlers-Danlos syndrome.

Symptoms

The symptoms of myocardial fibrosis can vary depending on the severity of the condition. They may include shortness of breath, fatigue, chest pain, and arrhythmia. In severe cases, it can lead to heart failure.

Diagnosis

Diagnosis of myocardial fibrosis typically involves a combination of medical history, physical examination, and various diagnostic tests. These tests may include echocardiography, cardiac MRI, and endomyocardial biopsy.

Treatment

Treatment for myocardial fibrosis aims to manage the underlying cause and alleviate symptoms. This may involve medications such as beta blockers, ACE inhibitors, and diuretics. In severe cases, surgical interventions such as heart transplantation may be necessary.

Prognosis

The prognosis for individuals with myocardial fibrosis can vary greatly depending on the underlying cause and the severity of the condition. Early detection and treatment can significantly improve the prognosis.

See also

• Cardiovascular disease
• Heart failure
• Cardiomyopathy

Myocardial fibrosis Resources
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