Myoinositol
Myo-Inositol is a type of sugar alcohol that is involved in various biological processes. It is a member of the vitamin B complex and is often referred to as vitamin B8, although it is not officially recognized as a vitamin because it can be synthesized by the human body.
Structure and Synthesis[edit | edit source]
Myo-Inositol is a cyclohexanehexol, a polyol that contains six hydroxyl groups. It is one of nine possible stereoisomers of inositol. In the human body, myo-inositol is synthesized from glucose-6-phosphate (G6P) in a two-step process that involves the enzymes inositol-3-phosphate synthase and inositol monophosphatase.
Biological Functions[edit | edit source]
Myo-Inositol plays a crucial role in various biological functions. It serves as a structural basis for a number of secondary messengers in eukaryotic cells, including inositol phosphates, phosphatidylinositol (PI) and phosphatidylinositol phosphate (PIP). These molecules are involved in a variety of cellular processes, such as cell growth, apoptosis, cell migration, endocytosis, and cell differentiation.
In addition, myo-inositol is a critical component of the structural lipids phosphatidylinositol (PI) and its various phosphates, the phosphatidylinositol phosphate (PIP) lipids.
Clinical Significance[edit | edit source]
Myo-Inositol has been studied for its potential therapeutic effects in a variety of medical conditions. It has been suggested to have benefits in conditions such as polycystic ovary syndrome (PCOS), lung cancer, panic disorder, and obsessive-compulsive disorder (OCD). However, more research is needed to confirm these findings and to fully understand the mechanisms of action of myo-inositol in these conditions.
See Also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD