NJK14047

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Chemical compound


NJK14047
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NJK14047 is a chemical compound that has been studied for its potential therapeutic effects, particularly in the context of neurodegenerative diseases. It is known for its role as a modulator of neurotrophic factors, which are crucial for the survival, development, and function of neurons.

Chemical Structure[edit | edit source]

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Chemical structure of NJK14047

NJK14047 is characterized by its complex molecular structure, which includes a piperazine ring and a trifluoromethyl group. The presence of these functional groups is significant for its biological activity, influencing its interaction with various biological targets.

Mechanism of Action[edit | edit source]

NJK14047 functions primarily by modulating the activity of neurotrophic factors. These factors, such as nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF), play a pivotal role in neuronal health. By influencing these pathways, NJK14047 may help in promoting neuronal survival and regeneration, which is particularly beneficial in conditions like Alzheimer's disease and Parkinson's disease.

Potential Therapeutic Applications[edit | edit source]

The primary interest in NJK14047 lies in its potential application in treating neurodegenerative disorders. By enhancing the activity of neurotrophic factors, NJK14047 could potentially slow down or reverse the progression of diseases characterized by neuronal loss. Research is ongoing to determine its efficacy and safety in clinical settings.

Pharmacokinetics[edit | edit source]

The pharmacokinetic profile of NJK14047 is still under investigation. Understanding its absorption, distribution, metabolism, and excretion (ADME) is crucial for developing it as a therapeutic agent. Preliminary studies suggest that it has a favorable profile, but more research is needed to confirm these findings.

Safety and Efficacy[edit | edit source]

As with any potential therapeutic compound, the safety and efficacy of NJK14047 must be thoroughly evaluated through clinical trials. Initial studies have shown promise, but comprehensive trials are necessary to establish its therapeutic value and safety profile.

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Contributors: Prab R. Tumpati, MD