NLRP2

NLRP2 or NACHT, LRR and PYD domains-containing protein 2 is a protein that in humans is encoded by the NLRP2 gene. NLRP2 is a member of the NLRP family, which is known for its role in the regulation of programmed cell death.

Function

The protein encoded by this gene is a member of the NLRP family, which is known for its role in the regulation of programmed cell death (apoptosis). The NLRP2 protein is thought to have a regulatory role in the process of apoptosis. It is also involved in the maturation of the inflammatory interleukin-1β (IL-1β) molecule.

Clinical significance

Mutations in the NLRP2 gene have been associated with recurrent miscarriage and Beckwith-Wiedemann syndrome.

See also

• NLRP
• Apoptosis
• Interleukin 1 beta
• Recurrent Miscarriage
• Beckwith-Wiedemann Syndrome

External links

• NCBI Gene
• UniProt

NLRP2 Resources
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