Nafadotride
Nafadotride is a drug that acts as a selective antagonist for the D3 dopamine receptor. It was developed for the treatment of Schizophrenia, but was not pursued for this application. However, it has been found to be useful in scientific research.
Pharmacology[edit | edit source]
Nafadotride is a selective antagonist for the D3 dopamine receptor. This means it binds to these receptors and blocks their activation by dopamine, a neurotransmitter that is involved in many functions including mood, reward, and motor control. By blocking the activation of D3 receptors, nafadotride can alter the effects of dopamine in the brain.
Uses[edit | edit source]
While nafadotride was initially developed for the treatment of schizophrenia, it was not pursued for this application. However, it has been found to be useful in scientific research. Because of its selective action on D3 receptors, it can be used to study the role of these receptors in various brain functions and diseases.
Side Effects[edit | edit source]
As with any drug, nafadotride can have side effects. However, because it is primarily used in research and not in clinical practice, these side effects are not well documented.
See Also[edit | edit source]
References[edit | edit source]
| Nafadotride Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
