Nandrolone phenpropionate

Nandrolone phenpropionate (NPP), also known as nandrolone phenylpropionate, is a synthetic anabolic-androgenic steroid (AAS) and a derivative of testosterone. It is more commonly known by its most famous brand name, Durabolin.

Pharmacology

Nandrolone phenpropionate is a prodrug of nandrolone. Like testosterone, nandrolone is an androgen receptor agonist. It is not a substrate for 5α-reductase as it is not 5α-reduced, hence does not potentiate in androgenic tissues such as the skin, hair follicles, and prostate gland. This is in contrast to testosterone, and serves to improve the separation of its anabolic and androgenic effects.

Medical uses

Nandrolone phenpropionate has been used in the treatment of osteoporosis, breast cancer, and for other indications. It is no longer marketed for medical use in the United States.

Side effects

Side effects of nandrolone phenpropionate include symptoms of masculinization like acne, increased hair growth, voice changes, and increased sexual desire. The drug is a synthetic androgen and anabolic steroid and hence is an agonist of the androgen receptor, the biological target of androgens like testosterone and dihydrotestosterone (DHT).

Legal status

In the United States, nandrolone phenpropionate is classified as a Schedule III controlled substance under the Controlled Substances Act. Internationally, the drug is controlled under the United Nations' Single Convention on Narcotic Drugs.

See also

• List of androgens/anabolic steroids
• List of Schedule III drugs (US)