Neggram

Neggram is a brand name for the antibiotic drug Nalidixic Acid, which is used in the treatment of urinary tract infections caused by susceptible bacteria. It belongs to the class of quinolone antibiotics, which work by killing the bacteria that cause infections.

History

Neggram was first introduced in the 1960s as a treatment for urinary tract infections. It was one of the first quinolone antibiotics to be developed and has been used extensively in clinical practice since its introduction.

Mechanism of Action

Neggram works by inhibiting the DNA gyrase enzyme, which is essential for bacterial DNA replication. By inhibiting this enzyme, Neggram prevents the bacteria from replicating and spreading, thereby helping to clear the infection.

Uses

Neggram is primarily used to treat urinary tract infections caused by susceptible bacteria. It may also be used to treat other types of infections, as determined by a healthcare provider.

Side Effects

Like all medications, Neggram can cause side effects. Common side effects include nausea, vomiting, and diarrhea. More serious side effects can include allergic reactions, liver damage, and neurological effects such as dizziness and confusion.

Precautions

Before taking Neggram, patients should inform their healthcare provider if they have any allergies, are pregnant or breastfeeding, or have any other medical conditions. Neggram can interact with other medications, so patients should also inform their healthcare provider of any other medications they are taking.

See Also

• Quinolone antibiotics
• Urinary tract infection
• DNA gyrase