Neurotrophin 3

Neurotrophin 3 (also known as NT-3) is a protein that in humans is encoded by the NTF3 gene. It is a member of the neurotrophin family, which induces the survival, development, and function of neurons.

Function

Neurotrophin 3 is a neurotrophic factor, a type of molecule that helps to regulate the growth, survival, and differentiation of neurons. It is part of the neurotrophin family, which also includes nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), and neurotrophin-4 (NT-4).

NT-3 is unique among the neurotrophins in its ability to support the survival of both sensory neurons and motor neurons. It is crucial for the development and maintenance of the nervous system, and has been implicated in a variety of neurological disorders.

Clinical significance

Research has suggested that NT-3 may have therapeutic potential in neurological disorders such as Alzheimer's disease, Parkinson's disease, and Huntington's disease. It may also have applications in the treatment of spinal cord injury, stroke, and depression.

See also

• Neurotrophin
• Nerve growth factor
• Brain-derived neurotrophic factor
• Neurotrophin-4