Nevus lipomatosus superficialis

Nevus Lipomatosus Superficialis is a rare benign skin condition characterized by the presence of multiple, soft, skin-colored papules and nodules. It was first described by Hoffman and Zurhelle in 1921. The condition is typically present at birth or develops during early childhood.

Etiology

The exact cause of Nevus Lipomatosus Superficialis is unknown. However, it is believed to be a result of a developmental anomaly of the dermis, where mature fat cells infiltrate the dermis, replacing the normal collagen and elastin fibers.

Clinical Features

Nevus Lipomatosus Superficialis presents as multiple, soft, skin-colored or slightly yellowish papules and nodules. They are typically arranged in a linear or zosteriform pattern. The most common sites of involvement are the buttocks, lower back, and upper thighs. However, they can occur anywhere on the body. The lesions are usually asymptomatic, but they can cause cosmetic concern.

Diagnosis

The diagnosis of Nevus Lipomatosus Superficialis is primarily clinical, based on the characteristic appearance of the lesions. However, a skin biopsy may be performed to confirm the diagnosis. Histologically, the dermis shows clusters of mature fat cells interspersed among the collagen bundles.

Treatment

As Nevus Lipomatosus Superficialis is a benign condition, treatment is not necessary unless the lesions cause cosmetic concern or discomfort. In such cases, surgical excision or laser therapy may be considered.

Prognosis

The prognosis for Nevus Lipomatosus Superficialis is excellent. The condition is benign and does not affect the patient's overall health or lifespan. However, the lesions can cause cosmetic concern, and there is a small risk of malignant transformation.

File:Nevus lipomatosus superficialis.jpg

Nevus Lipomatosus Superficialis on the buttock

See Also

• Nevus
• Dermis
• Skin Biopsy

References

• Hoffman, E., & Zurhelle, E. (1921). Über einen naevus lipomatosus cutaneous superficialis der linken Glutaalgegend. Archiv für Dermatologie und Syphilis, 130(3-4), 327-333.
• Jones, E. W., & Marks, R. (1969). Naevus superficialis lipomatosus. A clinicopathological report of twenty cases. The British journal of dermatology, 81(12), 899-901.