Nicarbazin
Nicarbazin is a coccidiostat used in the poultry industry. It is a combination of two chemical compounds, 4,4'-dinitrocarbanilide (DNC) and 2-hydroxy-4,6-dimethylpyrimidine (HDP). Nicarbazin is primarily used to control coccidiosis, a parasitic disease that affects the intestinal tract of animals.
History[edit | edit source]
Nicarbazin was first developed in the 1950s by the pharmaceutical industry as a means to combat coccidiosis in poultry. It was one of the first coccidiostats to be introduced and has since been widely used in the poultry industry worldwide.
Mechanism of Action[edit | edit source]
The exact mechanism of action of Nicarbazin is not fully understood. However, it is believed that the DNC component interferes with the energy metabolism of the coccidia parasite, while the HDP component inhibits the synthesis of nucleic acids in the parasite.
Usage[edit | edit source]
Nicarbazin is administered to poultry in their feed. The recommended dosage varies depending on the specific needs of the flock and the severity of the coccidiosis outbreak. It is important to note that Nicarbazin should not be used in laying hens producing eggs for human consumption, as it can lead to egg discoloration and reduced hatchability.
Side Effects[edit | edit source]
Potential side effects of Nicarbazin include reduced feed intake, weight loss, and decreased egg production. In severe cases, it can cause toxicity and death in poultry. Therefore, it is crucial to monitor the health of the flock closely when administering this drug.
Regulatory Status[edit | edit source]
In the United States, Nicarbazin is regulated by the Food and Drug Administration (FDA). It is classified as a veterinary drug and its use is subject to specific regulations and restrictions.
See Also[edit | edit source]
 | This pharmacology-related article is a stub. You can help WikiMD by expanding it. |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
