Nitroxyl
Nitroxyl (also known as HNO) is a reactive nitrogen species that is a powerful reducing agent. It is the one-electron reduction product of nitric oxide (NO) and is isoelectronic with dioxygen. Nitroxyl can be formed from the reduction of nitric oxide or from the protonation of nitroxide (NO−). Nitroxyl is a powerful reducing agent, and it reacts with oxygen to form nitric oxide and water.
Chemistry[edit | edit source]
Nitroxyl is a reactive nitrogen species that is a powerful reducing agent. It is the one-electron reduction product of nitric oxide (NO) and is isoelectronic with dioxygen. Nitroxyl can be formed from the reduction of nitric oxide or from the protonation of nitroxide (NO−). Nitroxyl is a powerful reducing agent, and it reacts with oxygen to form nitric oxide and water.
Biological role[edit | edit source]
In biological systems, nitroxyl has been found to have a number of important roles. It is involved in the regulation of vascular tone, neurotransmission, and immune response. Nitroxyl can also react with a number of biological targets, including thiols, metals, and nucleophiles.
Medical applications[edit | edit source]
Due to its biological activity, nitroxyl has potential applications in medicine. It has been shown to have vasodilatory effects, and it may have potential as a treatment for heart failure. Nitroxyl donors have also been investigated for their potential as anticancer agents.
See also[edit | edit source]
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