Node

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Node (medicine)

A node in medicine refers to a small, often roundish, mass of tissue differing from its surroundings. Nodes can be found in various parts of the body, including the lymphatic system, where they are known as lymph nodes, and the nervous system, where they are referred to as neuronal nodes or nodes of Ranvier.

Lymph nodes[edit | edit source]

Lymph nodes are small, bean-shaped structures that produce and store cells that fight infection and disease. They are a vital part of the immune system. Lymph nodes are located throughout the body, but the largest groupings can be found in the neck, armpits, and groin.

Nodes of Ranvier[edit | edit source]

The nodes of Ranvier, also known as myelin sheath gaps, are small gaps in the insulating myelin sheath that surrounds the axons of many neurons. They play a crucial role in the conduction of nerve impulses.

Clinical significance[edit | edit source]

Nodes can become enlarged or inflamed due to infection, disease, or cancer. For example, lymphadenopathy refers to disease of the lymph nodes, in which they are abnormal in size, number, or consistency. Lymphadenitis is the inflammation of a lymph node.

See also[edit | edit source]

Node Resources
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Contributors: Prab R. Tumpati, MD